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LARRY LEE KEELEY

Curriculum Vitae

 

EDUCATION

B.S., University of Notre Dame, 1962
Major: Biology
Minor: Chemistry

Ph.D., Purdue University, 1966
Major: Entomology
Minor: Biochemistry-Physiology

Special Education: 1982
Workshop, Hormone Action and Molecular Endocrinology, Baylor College of Medicine, Houston, TX; Organizers: W.T. Schrader and B.W. O'Malley

PROFESSIONAL EXPERIENCE

1966 Assistant Professor, Entomology, Texas A&M University

1970 Associate Professor, Entomology, Texas A&M University

1976 Professor, Entomology, Texas A&M University

1985 Adjunct Professor, Biochemistry-Biophysics, Texas A&M University

1989 Member, Faculty of Molecular and Cellular Biology, Texas A&M University

1993 Professor, Faculty of Neurosciences, Texas A&M University

2006, Professor Emeritus, Department of Entomology, Texas A&M University

TEACHING

(Undergraduate Level)
Entomology 306: Insect Physiology

(Graduate Level)
Entomology 615: Insect Physiology
Entomology 620: Insect Biochemistry and Endocrinology

MS Students: 9

Ph.D. Students: 12

Post-Doctoral Students: 3

Senior Honors Research Students: 17

PROFESSIONAL AFFILIATIONS

American Association for the Advancement of Science

American Society of Biochemistry and Molecular Biology

Society for Integrative and Comparative Biology

Entomological Society of America

RESEARCH

Research interests include insect and crustacean neuroendocrine regulations of metabolism and reproduction.

SELECTED REFERREED, TECHNICAL PUBLICATIONS (74 total)

Keeley, L.L. (1972) Biogenesis of mitochondria: neuroendocrine effects on the development of respiratory functions in fat body mitochondria of the cockroach Blaberus discoidalis.  Archives of Biochemistry and Biophysics 153, 8-15.

Keeley, L.L. (1978) Development and endocrine regulation of mitochondrial cytochrome biosynthesis in the insect fat body.  Delta-aminolevulinic acid synthase.  Archives of Biochemistry and  Biophysics 187, 79-86.

Hayes, T.K. and Keeley, L.L. (1981) Cytochromogenic factor: a newly-discovered neuroendocrine agent stimulating mitochondrial cytochrome synthesis in the insect fat body.  General and Comparative Endocrinology 45, 115-124.

Hayes, T.K. and Keeley, L.L. (1984) Patterns and control of neurosecretion for the cytochromogenic hormone in Blaberus discoidalis cockroaches.  Journal of Experimental Biology 107, 49-58.

Hayes, T.K., Keeley, L.L. and Knight, D.W. (1986) Insect hypertrehalosemic hormone: Isolation and primary structure from Blaberus discoidalis cockroaches.  Biochemical Biophysical Research Communications 140, 674-678.

Keeley, L.L. and Hayes, T.K. (1987) Speculations on biotechnology applications for insect neuroendocrine research.  (Mini-Review).  Insect Biochemistry 17, 639-651.

Chan, S.-M., Rankin, S.M. and Keeley, L.L. (1988) Characterization of the molt stages in Penaeus vannamei: Setogenesis and hemolymph levels of total protein, ecdysteroids and glucose.  Biological Bulletin 175, 185-192.

Chung, J.-S. and Keeley, L.L. (1989) Evidence and bioassay for diuretic factors in the nervous system of larval Heliothis virescens (F.). Journal of Comparative Physiology 159, 359-370.

Bradfield, J.Y. and Keeley, L.L. (1989) Adipokinetic hormone gene sequence from Manduca sexta.  Journal of Biological Chemistry 264, 12791-12793.

Bradfield, J.Y., Lee, Y.-H. and Keeley, L.L. (1991) Cytochrome P450 family 4 in a cockroach: molecular cloning and regulation by hypertrehalosemic hormone.  Proceedings of the National Academy of Sciences, U.S.A. 88, 4558-4562.

Keeley, L.L., Chung, J.-S. and Hayes, T.K. (1992) Diuretic and antifeedant actions by Manduca sexta diuretic hormone in lepidopteran larvae.  Experientia 48, 1145-1148.

Lee, Y.-H. and Keeley, L.L. (1994) Hypertrehalosemic hormone effects on transcriptional activity in the fat body of the cockroach, Blaberus discoidalis.  Insect Biochemistry and Molecular Biology 24, 357-362.

Sowa, S.M., Lu, K.-H. Park, J.H. and Keeley, L.L. (1996) Physiological effectors of hyperglycemic neurohormone biosynthesis in an insect.  Molecular and Cellular Endocrinology 123, 97-105.

Lewis, D.K., Jezierski, M., Bradfield, J.Y. and Keeley, L.L.  (1997) Hypertrehalosemic hormone in a cockroach: molecular cloning and expression.  Molecular and Cellular Endocrinology, 130, 101-108.

Lu, K.-H., Bradfield, J.Y. and Keeley, L.L. (1999) Juvenile hormone inhibition of gene expression for cytochrome P4504C1 in adult females of the cockroach, Blaberus discoidalis. Insect Biochemistry and Molecular Biology, 29, 667-673.

Chen, M.-E., Lewis, D.K., Keeley, L.L. and Pietrantonio, P.V. (2004) cDNA cloning and transcriptional regulation of the vitellogenin receptor from the imported fire ant, Solenopsis invicta  Buren (Hymenoptera: Formicidae).  Insect Biochemistry and Molecular Biology 13, 195-204.

SELECTED BOOK CHAPTERS AND INVITED REVIEWS (18 total)

Keeley, L.L. (1978)  Endocrine Regulation of Fat Body Development and Function.  Annual Review of Entomology 23, 324-352.

Keeley, L.L. (1985)  Biochemistry and Physiology of the Insect Fat Body.  In: Comprehensive Insect Physiology, Biochemistry and Pharmacology, (Ed. Kerkut, G.A. and Gilbert, L.I.), vol. 3., pp. 211-248, Pergamon Press, NY.

Keeley, L.L. (1988)  Potential Applications of Neuroendocrine Research to Insect Control.  In: Biotechnology for Crop Protection:, (ed. Hedin, P.A., Menn, J.J. and Hollingworth, R.M.), American Chemical Society Series No. 379, pgs. 147-159.

Keeley, L.L., Hayes, T.K., Bradfield, J.Y. and Chung, J.S. (1989)  Neuropeptides in Insect Control. In: Proceedings of a Conference on Biotechnology, Biological Pesticides and Novel Plant-Pest Resistance for Insect Pest Management, (eds. Roberts, D.W. and Granados, R.R.) pps. 99-106, Boyce Thompson Institute for Plant Research, Ithaca, NY, July 18-20, 1988.  175 pgs.

Keeley, L.L. (1990)  Neuroendocrine Regulation of Fat Body Metabolism.  In: Cockroaches as Models for Neurobiology: Applications in Biomedical Research.  (eds. I. Huber, E.P. Masler and B. R. Rao), v. II, pps. 149-158. CRC Press, Boca Raton, FL, 326 pgs.

Keeley, L.L., Hayes, T.K. and Bradfield, J.Y. (1990)  Insect Neuroendocrinology: Its Past, Its Present; Future Opportunities.  In: Insect Neuroendocrinology and Neurophysiology • 1989 •, (ed. Borkovec, A.B. and Masler, E.P.), pp. 163-203, Humana, Clifton, NJ, 480 pgs.

Keeley, L.L., Hayes, T.K., Bradfield, J.Y. and Lee, Y.-H. (1991)  Metabolic Neuropeptides, In: Insect Neuropeptides (Ed. Menn, J.J., Kelly, T.J. and Masler, E.P.), pp. 65-82, Amer. Chem. Soc. Symp. Series No. 453.

Keeley, L.L., Bradfield, J.Y., Sowa, S.M., Lee Y.-H. and Lu K.-H. (1994) Physiological actions of the hypertrehalosemic hormone in cockroaches.  In: Perspectives in Comparative Endocrinology (eds. Davey, K.G., Peter, R.E. and Tobe, S.S.)  pgs. 475-485. National Research Council Canada, Ottawa.

 

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